ImmunologybioRxivPreprint
T-cell signaling relies on partial CD45-exclusion at sub-micron sized cellular contacts
Mateusz Kotowski, Daniel F. Heraghty, Markus Körbel…·Simon J. Davis
The paper shows that T-cell activation is initiated by partial CD45 exclusion at sub-micron contacts, leading to strong activation and cytotoxicity through small signaling changes.
3 citations