Emily E. Bacon

This paper identifies SigAb as a metal stress-responsive ECF σ factor in Acinetobacter baumannii, showing it directly regulates a small set of genes and indirectly controls hundreds involved in metal resistance and fitness.

The paper develops inducible gene expression systems for Escherichia coli and Acinetobacter baumannii, enabling cross-species functional studies of gene regulation.

The paper develops CRISPRtOE, a genome-scale overexpression platform for Proteobacteria, demonstrating its use in Escherichia coli and Zymomonas mobilis to identify antibiotic and engineering targets.

This study identifies genetic vulnerabilities and antibiotic sensitivities in Acinetobacter baumannii using CRISPRi, revealing key targets and interactions for therapeutic development.