Kevin S. Myers

This study shows that OxyR regulates oxidative stress in Zymomonas mobilis during oxic growth and anoxic fermentation, with its absence impairing growth and ethanol production in hydrolysate.

The paper analyzes metagenomes and metagenome-assembled genomes from microbial communities in a wastewater treatment plant under varying dissolved oxygen conditions to understand microbial adaptation to low-DO environments.

The paper identifies genomic targets for improving anaerobic chemical tolerance in Zymomonas mobilis using orthogonal gene perturbation screens and validates findings through gene deletions.

The paper analyzes metagenomes and MAGs from a wastewater treatment plant under varying DO conditions to study microbial adaptation to energy-efficient processes.

This paper identifies SigAb as a metal stress-responsive ECF σ factor in Acinetobacter baumannii, showing it directly regulates a small set of genes and indirectly controls hundreds involved in metal resistance and fitness.

This study identifies how altering translation in E. coli mitigates the growth inhibition caused by chemically stabilized G-quadruplexes.

The paper develops CRISPRtOE, a genome-scale overexpression platform for Proteobacteria, demonstrating its use in Escherichia coli and Zymomonas mobilis to identify antibiotic and engineering targets.

The paper introduces MuRCiS, a CRISPRi-Seq method to identify gene combinations critical for virulence in L. pneumophila, finding that lpg2888 and lpg3000 have redundant roles in macrophages, while lpg3000 is essential in amoebae.

This study identifies genetic interactions linking the PriA/PriB DNA replication restart pathway to double-strand DNA break repair in E. coli using transposon insertion sequencing and targeted experiments.

The paper deciphers the DNA-specificity code of ECF σ factors to predict their regulons and reveals their varied regulatory roles in bacterial gene regulation.

This study investigates the roles of PKA and HOG signaling in anaerobic xylose fermentation and stress tolerance in yeast engineered for biofuel production, finding that HOG1 mutations specifically enhance xylose usage while PKA activity affects growth but not xylose fermentation.