Amy B. Banta

The paper identifies surface receptor masking and internal defenses as barriers to phage therapy in Pseudomonas aeruginosa clinical isolates and presents strategies to overcome these barriers through phage engineering.

The paper identifies genomic targets for improving anaerobic chemical tolerance in Zymomonas mobilis using orthogonal gene perturbation screens and validates findings through gene deletions.

This paper identifies SigAb as a metal stress-responsive ECF σ factor in Acinetobacter baumannii, showing it directly regulates a small set of genes and indirectly controls hundreds involved in metal resistance and fitness.

This study identifies Pseudomonas aeruginosa genes whose partial knockdown increases vulnerability in a murine pneumonia model, highlighting potential targets for antibacterial strategies.

The paper uses double-CRISPRi to systematically analyze genetic interactions in Bacillus subtilis, identifying over 1000 interactions and revealing roles of paralogous genes in cell division.

The paper develops CRISPRtOE, a genome-scale overexpression platform for Proteobacteria, demonstrating its use in Escherichia coli and Zymomonas mobilis to identify antibiotic and engineering targets.

This study identifies genetic vulnerabilities and antibiotic sensitivities in Acinetobacter baumannii using CRISPRi, revealing key targets and interactions for therapeutic development.

This study identifies conditionally essential genes in Zymomonas mobilis for aerobic and anaerobic growth using CRISPRi-seq, revealing roles of DNA repair and respiratory complexes in energy coupling and isoprenoid biosynthesis.