Author

Miguel da Silva Padilha

University of CologneORCID 0000-0001-8141-7163Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1

Frequent Co-Authors

David Vı́lcheziD· 2 shared Irina DudanovaiD· 2 shared Rüdiger KleiniD· 2 shared Seda KoyuncuiD· 2 shared Andrei LeonoviD· 1 shared Armin GieseiD· 1 shared Christian GriesingeriD· 1 shared Dennis FeigenbutziD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersNeuroscience

David Vı́lchezORCID

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2 papers

Recent·Most cited

NeuroscienceEMBO Molecular MedicinePeer-reviewedJun 26, 2026

Anle138b ameliorates pathological phenotypes in mouse and cellular models of Huntington's disease

Miguel da Silva Padilha, Seda Koyuncu, Evangeline Chabanis…·Irina Dudanova

Anle138b reduces mHTT aggregates and improves disease phenotypes in HD cell and mouse models.

DOI 10.1038/s44321-026-00459-9

𝕏 PostBluesky

NeuroscienceLife Science AlliancePeer-reviewedAug 14, 2023

Neuroprotective effects of hepatoma-derived growth factor in models of Huntington's disease

Kerstin Voelkl, Sara Gutiérrez-Ángel, Sophie Keeling…·Irina Dudanova

This study shows that hepatoma-derived growth factor (HDGF) has neuroprotective effects in Huntington's disease models by reducing mutant Huntingtin toxicity and aggregation.

7 citations

𝕏 PostBluesky