Author

Parastoo Khoshakhlagh

Harvard UniversityORCID 0000-0001-8183-2340Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:human· 2 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Cory J. SmithiD· 2 shared George McDonald ChurchiD· 2 shared Hannu MyllykallioiD· 2 shared Khaled Said· 2 shared Marc GüelliD· 2 shared Oscar CastanoniD· 2 shared Raphaël FerreiraiD· 2 shared Alex H. M. NgiD· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersSynthetic Biology

Cory J. SmithORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Synthetic BiologyNucleic Acids ResearchPeer-reviewedApr 1, 2020

Enabling large-scale genome editing by reducing DNA nicking

Cory J. Smith, Oscar Castanon, Khaled Said…·George McDonald Church

This paper develops dead-Cas9 base editors that enable large-scale genome editing in human cells by reducing DNA nicking, allowing editing of over 10,000 loci.

80 citations

humanCRISPR screen

𝕏 PostBluesky

Synthetic BiologybioRxivPreprintFeb 3, 2020

CRISPR-mediated biocontainment

Oscar Castanon, Cory J. Smith, Parastoo Khoshakhlagh…·George McDonald Church

The paper develops CRISPR-based biocontainment circuits using transposable elements to induce cell death and create kill-switches for controlling cell lines.

6 citations

humanexperimental assay

𝕏 PostBluesky