Author

Cory J. Smith

Harvard UniversityORCID 0000-0001-5261-2250Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Synthetic Biology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:CRISPR screen· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

George McDonald ChurchiD· 3 shared Khaled Said· 3 shared Amanda HornickiD· 2 shared Hannu MyllykallioiD· 2 shared Marc GüelliD· 2 shared Oscar CastanoniD· 2 shared Parastoo KhoshakhlaghiD· 2 shared Raphaël FerreiraiD· 2 shared

Activity by Year

2019-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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3 shared papersSynthetic Biology

George McDonald ChurchORCID

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3 papers

Recent·Most cited

Synthetic BiologyNucleic Acids ResearchPeer-reviewedApr 1, 2020

Enabling large-scale genome editing by reducing DNA nicking

Cory J. Smith, Oscar Castanon, Khaled Said…·George McDonald Church

This paper develops dead-Cas9 base editors that enable large-scale genome editing in human cells by reducing DNA nicking, allowing editing of over 10,000 loci.

80 citations

humanCRISPR screen

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Synthetic BiologybioRxivPreprintFeb 3, 2020

CRISPR-mediated biocontainment

Oscar Castanon, Cory J. Smith, Parastoo Khoshakhlagh…·George McDonald Church

The paper develops CRISPR-based biocontainment circuits using transposable elements to induce cell death and create kill-switches for controlling cell lines.

6 citations

humanexperimental assay

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Molecular BiologybioRxivPreprintFeb 22, 2019

Rapid and scalable in vitro production of single-stranded DNA

Dionis Minev, Richard Guerra, Jocelyn Y. Kishi…·William M. Shih

This paper describes a method for producing high-purity single-stranded DNA for various applications.

3 citations

humanDNA methylation

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