Author

Yongxian Zhuang

Mayo ClinicORCID 0000-0001-8219-7764Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:metagenomics· 1 Assay:proteomics· 1

Frequent Co-Authors

Adrienne D. CoxiD· 1 shared Andrew M. WatersiD· 1 shared Bjoern PapkeiD· 1 shared Channing J. DeriD· 1 shared Chia‐Chen LiuiD· 1 shared Christine SersiD· 1 shared Clint A. StalneckeriD· 1 shared Cole P MartiniD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperCancer Biology

Adrienne D. CoxORCID

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintAug 11, 2026

Concurrent AXL inhibition enhances RAS and ERK inhibitor efficacy in KRAS-mutant pancreatic and lung cancer

Yan Ming Ching, Shruthi Narayanan, Jeffrey A. Klomp…·Bjoern Papke

This study shows that combining AXL inhibition with RAS or ERK inhibitors enhances efficacy in KRAS-mutant cancers by overcoming resistance mechanisms.

1 citation

humanmouse

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NeuroscienceNature NeurosciencePeer-reviewedDec 16, 2021

TREM2 interacts with TDP-43 and mediates microglial neuroprotection against TDP-43-related neurodegeneration

Manling Xie, Yong Liu, Shunyi Zhao…·Long‐Jun Wu

This study identifies a novel interaction between TREM2 and TDP-43, showing TREM2 mediates microglial neuroprotection against TDP-43-related neurodegeneration.

157 citationstop 1%

mouseexperimental assay

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