Spike and host glycan determinants of HKU1 airway tropism
Robert Creutznacher, Louisa E. Wallace, Oliver J. Debski-Antoniak…·Raoul J. de Groot
This study identifies spike and host glycan determinants of HKU1 airway tropism by showing preferential binding to 9-O-acetylated 2,8-linked disialosides and structural insights into ligand recognition.