Doryen Bubeck

This study defines the mechanism of BSAP-1 toxin action, showing receptor recognition and protease-activation lead to pore formation in target cells.

This study shows that C9, a component of membrane attack complexes, forms non-cytolytic intracellular aggregates that promote inflammation and EC activation through aggrephagy and NF-κB activation.

The paper uses AF2-multimer to accurately predict both canonical and atypical ATG8 binding motifs in proteins, including those in pathogens and plant hosts.

The paper reveals how CP12 regulates the Calvin cycle by structurally pre-ordering itself before binding PRK and influencing GAPDH activity based on redox state and NAD availability.