Author

Brintha Selvarajah

University College LondonORCID 0000-0001-8342-9117Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:statistical model· 1

Frequent Co-Authors

Delphine GuillotiniD· 1 shared Greg ContentoiD· 1 shared Jo-Anne A M WilsoniD· 1 shared Katiuscia BianchiiD· 1 shared Manuela PlatéiD· 1 shared Marcello TrevisaniiD· 1 shared Rachel Clare ChambersiD· 1 shared Valle MoralesiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperCell Biology

Delphine GuillotinORCID

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1 paper

Recent·Most cited

Cell BiologyJCI InsightPeer-reviewedAug 13, 2024

Pyruvate metabolism dictates fibroblast sensitivity to GLS1 inhibition during fibrogenesis

Greg Contento, Jo-Anne A M Wilson, Brintha Selvarajah…·Rachel Clare Chambers

This study shows that pyruvate metabolism affects fibroblast response to GLS1 inhibition during fibrosis, suggesting combined targeting of pyruvate metabolism and glutaminolysis as a therapeutic strategy.

23 citationstop 3%

humanbulk RNA-seq

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