Alexander N. Freiberg

This study shows that Powassan virus infects mouse testes and that phagocytic cells help limit viral infection in the male reproductive tract.

This study recovers Ghana virus, an African bat Henipavirus, and shows it has restricted receptor tropism and attenuated pathogenicity compared to Nipah virus.

This study identifies TRIM7 as an E3-ubiquitin ligase that ubiquitinates SARS-CoV-2 M protein to inhibit apoptosis and viral replication.

This paper develops tetracistronic minigenomes for henipaviruses to model their life cycle outside high biocontainment, revealing Cedar virus replicase promiscuity and functional GhV replicase with antiviral efficacy.

This study identifies SARS-CoV-2 proteases NSP3 and NSP5 cleaving IRF3, NLRP12, and TAB1, which modulate inflammatory pathways, and explores implications for disease across species and potential reservoir hosts.