Flavia Mancini

Multi-timescale dynamics organize descending pain modulation

The paper investigates the multi-timescale dynamics of pain-modulating neurons in the RVM, showing distinct rapid and slow activity patterns during and between stimuli.

Moment-to-Moment Pain Variability Predicts Pain Chronification

The paper shows that reduced moment-to-moment pain variability predicts the development of chronic pain from subacute pain.

Enhanced behavioural and neural sensitivity to punishments in chronic pain and fatigue

This study identifies increased punishment sensitivity and specific neural activity patterns in chronic pain and fatigue patients during decision-making tasks.

Confidence of probabilistic predictions modulates the cortical response to pain

The paper investigates how confidence in probabilistic pain predictions modulates EEG responses to noxious stimuli using a temporal statistical learning task.

Learning the statistics of pain: computational and neural mechanisms

This study investigates how humans learn statistical patterns of pain over time and identifies neural correlates of Bayesian inference and uncertainty in pain prediction.

Prefrontal responses during proactive and reactive inhibition are differentially impacted by stress in anorexia and bulimia nervosa

The paper examines how stress affects proactive and reactive inhibition in bulimia nervosa and anorexia nervosa binge-purging subtype using fMRI and behavioral tasks.

The mechanism of analgesia in Nav1.7 null mutants

This study identifies opioid-dependent inhibition of neurotransmitter release as the primary mechanism of analgesia in NaV1.7 null mutants in mice and humans.

Fine-grained mapping of cortical somatotopies in chronic Complex Regional Pain Syndrome

This study uses functional MRI to show that S1 representations of the CRPS-affected hand are preserved, challenging the idea that reorganization underlies the condition.

Within-finger maps of tactile and nociceptive input in the human parietal cortex

This study uses fMRI to investigate within-finger maps of nociceptive and tactile input in the human parietal cortex, finding a nociceptive map in hIP1 but not tactile maps.

Characterising the short-term habituation of event-related evoked potentials

This study investigates how different event-related potential (ERP) components habituate with repeated somatosensory stimuli, showing similar decay patterns for both lateralised and vertex waves.