Sihui Asuka Guan

The paper shows that juvenile C. elegans generate symmetric motor patterns through an asymmetric motor circuit, with dorsal bending driven by synaptic wiring and ventral bending via extrasynaptic signaling from premotor interneurons.

The paper identifies multiple rhythm generators in C. elegans forward locomotion through optogenetic and ablation experiments, showing coordinated oscillations between body regions.

The paper identifies class A motor neurons in C. elegans as intrinsic oscillators driving reverse locomotion without premotor interneurons.