Tosif Ahamed

This study identifies a master neuron in C. elegans that modulates forward and backward movement through tonic and phasic activity at different timescales.

The paper shows that juvenile C. elegans generate symmetric motor patterns through an asymmetric motor circuit, with dorsal bending driven by synaptic wiring and ventral bending via extrasynaptic signaling from premotor interneurons.

The paper reconstructs the post-embryonic maturation of the C. elegans motor circuit using electron microscopy, showing how structural rewiring maintains functional output during development.