Yangning Lu

Dense, Continuous Membrane Labeling and Expansion Microscopy Visualization of Ultrastructure in Tissues

The paper introduces umExM, a method for dense membrane labeling and expansion microscopy to achieve nanoscale visualization of membranes in tissues, demonstrating resolution down to ~35 nm.

Extrasynaptic signaling enables an asymmetric juvenile motor circuit to produce a symmetric gait

The paper shows that juvenile C. elegans generate symmetric motor patterns through an asymmetric motor circuit, with dorsal bending driven by synaptic wiring and ventral bending via extrasynaptic signaling from premotor interneurons.

Post-embryonic maturation of the C. elegans motor circuit

The paper reconstructs the post-embryonic maturation of the C. elegans motor circuit using electron microscopy, showing how structural rewiring maintains functional output during development.

A descending pathway facilitates undulatory wave propagation in Caenorhabditis elegans through gap junctions

The paper investigates how AVB-B gap junctions in C. elegans facilitate undulatory wave propagation during forward locomotion through intrinsic motor neuron oscillations and proprioceptive coupling.

Excitatory Motor Neurons are Local Central Pattern Generators in an Anatomically Compressed Motor Circuit for Reverse Locomotion

The paper identifies class A motor neurons in C. elegans as intrinsic oscillators driving reverse locomotion without premotor interneurons.

Neuroendocrine Modulation Sustains the C. elegans Forward Motor State

The paper identifies a neuroendocrine neuron, RID, in C. elegans that sustains forward movement through the neuropeptide FLP-14.