Susanne Huch

This paper introduces s5PSeq, a streamlined protocol for rapid antimicrobial sensitivity testing using 5P mRNA degradation intermediates, demonstrating its clinical utility in identifying resistant Clostridioides difficile isolates.

The paper shows that ribosomes modulate transcriptome abundance through frameshifts and out-of-frame mRNA decay in yeast under poor nutritional conditions, with conservation across species.

The paper analyzes RNA degradation in microbiome samples to study ribosome dynamics and species-specific responses to stress and drugs.

The paper shows that Not1 and Not4 oppositely regulate mRNA solubility, affecting co-translational dynamics in yeast.