Author

Lisa Boinon

University of ArizonaORCID 0000-0001-8650-1014Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:drug response / drug discovery· 3 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell-cell communication· 1 Organism:mouse· 1 Assay:protein structure· 1 Organism:rat· 1

Frequent Co-Authors

Aubin MoutaliD· 3 shared Dongzhi RaniD· 3 shared Harrison J. StrattoniD· 3 shared Kimberly GómeziD· 3 shared Rajesh KhannaiD· 3 shared Cynthia L. MaduraiD· 2 shared Samantha Perez‐MilleriD· 2 shared Shizhen LuoiD· 2 shared

Activity by Year

2020-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersNeuroscience

Aubin MoutalORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Phenylhydrazone-based Endoplasmic Reticulum Proteostasis Regulator Compounds with Enhanced Biological Activity

Gabriel M. Kline, Lisa Boinon, Adrian M. Guerrero, Sergei Kutseikin, Gabrielle Cruz, Marnie P Williams, Ryan J Paxman, William E. Balch, Jeffery W. Kelly, Ting‐Wei Mu, R. Luke Wiseman

This study identifies AA263 analogs that enhance ER proteostasis by targeting ER protein disulfide isomerases, correcting protein misfolding in disease models.

bioRxiv · Apr 4, 2025Cell Biology

Identification and targeting of a unique NaV1.7 domain driving chronic pain

Kimberly Gómez, Harrison J. Stratton, Paz Duran, Santiago Loya‐López, Cheng Wu Tang, Aida Calderón‐Rivera, Liberty François‐Moutal, May Khanna, Cynthia L. Madura, Shizhen Luo, Bryan D. Mckiver, Edward Choi, Dongzhi Ran, Lisa Boinon, Samantha Perez‐Miller, , Rajesh Khanna

The paper identifies a unique NaV1.7 domain that can be targeted to produce analgesia by disrupting its interaction with CRMP2.

Proceedings of the National Academy of Sciences · Jul 27, 2023Peer-reviewedNeuroscience

SARS-CoV-2 Spike protein hijacks VEGF-A/Neuropilin-1 receptor signaling to induce analgesia

Aubin Moutal, Laurent Martin, Lisa Boinon, Kimberly Gómez, Dongzhi Ran, Yuan Zhou, Harrison J. Stratton, Song Cai, Shizhen Luo, Kerry Beth Gonzalez, Samantha Perez‐Miller, Amol M. Patwardhan, Mohab M. Ibrahim, Rajesh Khanna

This study shows that SARS-CoV-2 Spike protein blocks VEGF-A/NRP-1 signaling, reducing pain and potentially contributing to asymptomatic transmission.

Pain · Oct 1, 2020Peer-reviewedNeuroscience

Studies on CRMP2 SUMOylation-deficient transgenic mice identify sex-specific NaV1.7 regulation in the pathogenesis of chronic neuropathic pain

Aubin Moutal, Song Cai, Jie Yu, Harrison J. Stratton, Aude Chefdeville, Kimberly Gómez, Dongzhi Ran, Cynthia L. Madura, Lisa Boinon, Maira Soto, Yuan Zhou, Zhiming Shan, Lindsey A. Chew, Kathleen E. Rodgers, Rajesh Khanna

This study shows that preventing CRMP2 SUMOylation reduces mechanical allodynia in female neuropathic pain models but not in males or other pain types.

Pain · Jun 19, 2020Peer-reviewedNeuroscience