A non-vesicular Argonaute protein is transmitted from nematode to mouse and is important for parasite survival
Kyriaki Neophytou, Isaac Martínez-Ugalde, Thomas M. Fenton, E. Douglas Robertson, Lewis J. Strachan, V Jayaraman, Yvonne M. Harcus, Chanel Milène Naar, David Wright, Daniel R. G. Price, Ruby F. White, Mike Evans, José Roberto Bermúdez‐Barrientos, Hanchen Li, Rick M. Maizels, , Amy H. Buck
This study identifies an extracellular Argonaute protein from a parasitic nematode that can be internalized by mouse cells and shows it can be targeted for vaccine development.
EMBO Reports · Dec 9, 2025Peer-reviewedMolecular Biology