Yurong Wen

This paper develops a genetically encoded fluorescent biosensor for extracellular L-lactate and demonstrates its use in imaging in cultured mammalian cells and brain tissue.

This paper develops improved photocleavable proteins with faster and more efficient dissociation for better optogenetic control.

The paper develops two high-performance genetically encoded biosensors for citrate imaging in mammalian cells, showing their ability to detect both steady-state and perturbed citrate concentrations.