ImmunologyCell Host & MicrobePeer-reviewed
Strong sustained type I IFN signaling acts cell intrinsically to impair IFNγ responses and cause tuberculosis susceptibility
Stefan A. Fattinger, Parisi Bianca, Roberto A. Chavez…·Russell E. Vance
The paper shows that sustained type I IFN signaling in infected macrophages impairs IFNγ responses, leading to tuberculosis susceptibility.