Author
University Health NetworkORCID 0000-0001-8874-2874Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Qiang Liu, Milena Gojsevic, Angelica Varesi…·Jean CY Wang
This study shows that PLK1 inhibition eradicates quiescent leukemia stem cells through a non-canonical mechanism involving microtubule and endolysosomal disruption, distinct from its canonical mitotic function.
Joana L. Araújo, Elvin Wagenblast, Véronique Voisin…·John Edgar Dick
This study shows FLT3 is essential for ITD-mutated leukemic stem cells but not for normal hematopoietic stem cells, supporting targeted therapies for AML.
Erwin M. Schoof, Benjamin Furtwängler, Nil Üresin…·Bo Torben Porse
The paper presents a workflow for single-cell proteomics to study cellular heterogeneity in leukemia, demonstrating the ability to quantify thousands of proteins per cell.
Elvin Wagenblast, Maria Azkanaz, Sabrina A. Smith…·Eric R. Lechman
The paper develops a method to efficiently edit LT-HSCs at single-cell resolution and demonstrates distinct functional outcomes of GATA1 editing.