Ying Liu

Adipose GPD2 Couples Glycolytic Signals to Epigenetic Control of Metabolic Homeostasis

This study identifies GPD2 as a key regulator linking glycolytic signals to epigenetic control of thermogenesis and metabolic homeostasis in adipose tissue.

Bone Mechanosensing Dictates Hematopoietic Stem Cell Fate and Immune Homeostasis

This study shows that bone mechanosensing influences HSC fate and immune homeostasis by directing lymphoid or myeloid differentiation through Piezo1-dependent pathways.

GYS2 Promotes the Progression of Aortic Dissection and Aortic Aneurysm via C5a/NF-κB-Mediated Pro-Inflammatory Macrophage Polarization

This study shows that GYS2 promotes aortic dissection and aneurysm by driving pro-inflammatory macrophage polarization through the C5a/NF-κB pathway.

Liver biopsy confirms precise and efficient correction of SERPINA1 after in vivo Base Editing in a Patient with Alpha-1 Antitrypsin Deficiency

Liver biopsy after PI*ZZ gene correction therapy reveals efficient and accurate base editing.

Digital Twin Brain simulation and manipulation of a functional brain network underlying mental illness

The paper develops a digital twin brain model that simulates and manipulates functional brain networks to predict mental illness symptoms and responses to interventions.

Plasma Ficolins Enable Liver Macrophages to Capture Blood-Borne Bacteria by Recognizing Capsular Polysaccharides

This study shows plasma ficolins enable liver macrophages to capture blood-borne bacteria by recognizing capsular polysaccharides, enhancing immune response against encapsulated bacteria.