Tony T. Wang

This study shows that immunity from previous infection or vaccination does not always prevent brain infection by antigenically distinct SARS-CoV-2 variants in animal models.

This study investigates the entry mechanisms of seasonal human coronaviruses NL63, 229E, and HKU1 using pseudoviruses and cell lines expressing ACE2, APN, or TMPRSS2, revealing endocytosis as the entry route and specific protease and receptor requirements.

The paper uses hamster sera to map antigenic differences among SARS-CoV-2 variants, showing JN.1 has significant antigenic divergence from XBB.1.5.

The paper synthesizes a shorter yeast chromosome and studies its fusion with other chromosomes, revealing new 3D structural interactions and Red1 binding patterns.

The paper analyzes SARS-CoV-2 genomic features to identify targets for vaccine development through codon pair deoptimization.