Lauren G. Koch

This study shows that early life exercise increases energy expenditure and BAT thermogenic capacity regardless of inborn fitness, while inborn fitness affects BAT proteome composition.

The paper identifies enhancer architecture differences in skeletal muscle between high and low cardiorespiratory fitness rats, linking them to gene expression and metabolic traits.

This study shows early-life exercise training can mitigate low inborn cardiorespiratory fitness effects, but molecular adaptations vary based on innate fitness.

This study examines how cardiorespiratory fitness affects epigenetic aging in different organs of rats, finding organ-specific and common changes in DNA methylation.

The paper shows aerobic capacity and exercise enhance bile acid metabolism, which is critical for reducing hepatic steatosis in mice.

This study shows metformin induces different mitochondrial remodeling in rat skeletal muscle based on baseline aerobic capacity and muscle type.

The paper examines how aging and aerobic capacity interact to affect metabolites in serum, muscle, and adipose tissue in rats, showing distinct metabolic changes in different tissues.

The paper identifies genomic regions under differential selection between two rat lines with divergent aerobic running capacity using SNP arrays and genome sequencing.