Mona Batish

This study identifies a defect in MMEJ repair in SMARCB1-deficient tumors, leading to hyper-dependence on the FA/BRCA pathway, which can be targeted for therapy.

The paper identifies LANCL1-AS1 as a lncRNA that declines with age in human skeletal muscle, reduces mitochondrial activity, and impairs myogenesis by shortening mt-mRNA poly(A) tails.

This study presents Cryo-EM structures of GdpP, revealing its conformational dynamics and allosteric regulation mechanism, with implications for antibiotic resistance.

EVRCEPT predicts RNA enrichment in extracellular vesicles using sequence features and provides RBP interactions, aiding in therapeutic RNA design.

The paper identifies factors influencing RNA sorting into extracellular vesicles, finding size and structuredness significantly affect enrichment of circular and linear RNAs.

SPIRFISH detects protein and RNA in single nanoparticles, revealing variability in structure and RNA packaging efficiency.

The paper profiles RNA in brain tissue and derived extracellular vesicles from SIV-infected macaques to identify dysregulated RNAs and their potential roles in CNS pathology.

The paper shows sex chromosomes can evolve from autosomes through two genes: one suppressing female function and one promoting male function.