Brendan Dolan

Airway Secretory Cells Contain Both a Perinuclear Golgi Ribbon and Dispersed Golgi Satellites

The paper examines the Golgi structure in airway secretory cells, finding a unique combination of a perinuclear Golgi ribbon and dispersed Golgi satellites, independent of mucin production levels.

Degradation of the intestinal mucus layer by the ETEC protease EatA is species specific determined by the structure of the MUC2 mucin

The paper shows ETEC protease EatA degrades human MUC2 mucin specifically, enabling bacterial infection by disrupting the intestinal mucus layer.

BPP43_05035 is a Brachyspira pilosicoli cell surface adhesin that weakens the integrity of the epithelial barrier during infection

This study identifies BPP43_05035 as a Brachyspira pilosicoli adhesin that disrupts epithelial tight junctions, increasing barrier permeability during infection.