Author

Vasil D’Ambrosio

Novo Nordisk FoundationORCID 0000-0001-9151-6747Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Organism:fungi (other)· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1 Approach:statistical model· 1 Organism:yeast· 1

Frequent Co-Authors

Brian King Himm Mo· 1 shared Eleonora DoreiD· 1 shared Francesca AmbriiD· 1 shared Jay D. KeaslingiD· 1 shared Jean‐Marie Mouillon· 1 shared Jolanda ter HorstiD· 1 shared Katherina García VanegasiD· 1 shared Marcel A. van den BroekiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperSynthetic Biology

Brian King Himm Mo

Mutual co-authors in cluster

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2 papers

Recent·Most cited

RoCi - A Single Step Multi-Copy Integration System Based on Rolling-Circle Replication

Martzel Antsotegi-Uskola, Vasil D’Ambrosio, Brian King Himm Mo, Zofia Dorota Jarczynska, Katherina García Vanegas, Martí Morera-Gómez, Xinhui Wang, Thomas Ostenfeld Larsen, Jean‐Marie Mouillon, Uffe Hasbro Mortensen

The paper introduces RoCi, a method for integrating multiple directly repeated gene-expression cassettes into a defined genomic locus in fungi, resulting in stable and high-yield production of metabolites and enzymes.

Nucleic Acids Research · Dec 17, 2025Peer-reviewedSynthetic Biology

Regulatory control circuits for stabilizing long-term anabolic product formation in yeast

Vasil D’Ambrosio, Eleonora Dore, Roberto Di Blasi, Marcel A. van den Broek, Suresh Sudarsan, Jolanda ter Horst, Francesca Ambri, Morten Otto Alexander Sommer, Peter Rugbjerg, Jay D. Keasling, Robert Mans, Michael Krogh Jensen

The paper designs synthetic control circuits in yeast to stabilize vanillin-β-glucoside production over multiple generations, achieving higher yields in fermentation.

Metabolic Engineering · Jul 24, 2020Peer-reviewedSynthetic Biology