Author

Yurika Otoki

Tohoku UniversityORCID 0000-0001-9172-2161Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Assay:metabolomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1 Organism:rat· 1

Frequent Co-Authors

James A. OlzmanniD· 2 shared Shunji KatoiD· 2 shared Ameer Y. TahaiD· 1 shared Anna GrekaiD· 1 shared Anthony E. ValenzuelaiD· 1 shared Anthony S. WexleriD· 1 shared Benjamin S. StyleriD· 1 shared Christopher WallisiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersCell Biology

James A. OlzmannORCID

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3 papers

Recent·Most cited

Cell BiologybioRxivPreprintJul 20, 2026

Double-bond geometry determines fatty acid metabolic fate and ferroptosis sensitivity

Cynthia A. Harris, Shunji Kato, Yurika Otoki…·James A. Olzmann

This study shows that fatty acid double-bond geometry affects metabolic fate and ferroptosis sensitivity by altering lipid composition and enzyme recognition.

DOI 10.64898/2026.07.17.739092

metabolomicsexperimental assay

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Cell BiologyNature Cell BiologyPeer-reviewedOct 29, 2025

FSP1-mediated lipid droplet quality control prevents neutral lipid peroxidation and ferroptosis

Mike Lange, Michele Wölk, Vivian Wen Li…·James A. Olzmann

This study identifies FSP1 as a critical regulator of lipid droplet quality control, preventing neutral lipid peroxidation and ferroptosis by recycling CoQ10.

69 citationstop 1%

metabolomicsexperimental assay

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NeurosciencebioRxivPreprintFeb 16, 2022

Pro-resolving lipid mediators within brain esterified lipid pools are reduced in female rats chronically exposed to traffic-related air pollution or genetically susceptible to Alzheimer's Disease phenotype

Qing Xiang Shen, Nuanyi Liang, Kelley T. Patten…·Ameer Y. Taha

This study finds that female rats with Alzheimer's Disease risk genes or exposed to traffic-related air pollution show reduced brain esterified pro-resolving lipid mediators, suggesting sex-specific impacts on inflammation resolution.

3 citations

ratstatistical model

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