Author

Matthias Versele

ORCID 0000-0001-9274-6579Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Assay:proteomics· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Bernard ThienpontiD· 1 shared Chris Van den HauteiD· 1 shared Eline VonckiD· 1 shared Frauke ChristiD· 1 shared Hugo KlaasseniD· 1 shared Kenneth W. Young· 1 shared Liesbeth Steegmans· 1 shared Marnik NijsiD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Bernard ThienpontORCID

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2 papers

Recent·Most cited

Protein aggregation inhibitors induce divergent transcriptional responses in a cellular model of a-synuclein seeded aggregation

Paulien Van Minsel, Chris Van den Haute, Eline Vonck, Shirine Hentati, Michele Curcio, Xinran Song, Qian Yu, Matthias Versele, Kenneth W. Young, Patrick Chaltin, Bernard Thienpont, Veronique Daniëls, Veerle Baekelandt, Wouter Peelaerts

The paper evaluates three Syn aggregation inhibitors in a cellular model of a-synuclein aggregation using single-cell RNA sequencing to identify transcriptional changes and potential druggable pathways.

npj Parkinson s Disease · Aug 26, 2026Peer-reviewedNeuroscience

HDAC inhibitors rescue MeCP2T158M speckles in a high content screen

Rodrigo Lata, Liesbeth Steegmans, Ranie Kellens, Marnik Nijs, Hugo Klaassen, Matthias Versele, Frauke Christ, Zeger Debyser

The paper screens FDA-approved drugs and compounds to identify small molecules that rescue MeCP2-T158M speckle formation in NIH3T3 cells, finding HDAC inhibitors as effective rescuers.

bioRxiv · Nov 2, 2023 · PreprintNeuroscience