Kenneth Lindegaard Madsen

This study demonstrates that vertical climbing in mice is a reliable and translationally relevant measure of pain-related functional impairment across multiple pain models.

The paper identifies Rab2, Syd/dJIP3/4, and RUFY as key regulators of retrograde axonal transport of dense core vesicles in Drosophila, showing distinct roles in DCV motility and sorting.

This study identifies venom-derived SSTR4 agonists as potential non-opioid therapeutics for peripheral pain conditions.

The paper identifies membrane-interaction sites in intrinsically disordered regions of transmembrane proteins using peptide arrays and fluorescent liposomes, revealing their role in disease.

The paper identifies amphipathic helix 8 as a driver of constitutive GPCR endocytosis through membrane curvature association.

The paper investigates glutamate receptor-dependent cytosolic acidification in hippocampal neurons, showing it involves both Ca2+ and passive proton influx mechanisms.

This paper develops AAV-delivered dimeric peptide inhibitors of PICK1 to alleviate neuropathic pain in mice, showing long-term relief without adverse effects.

This study uses dopamine sensors and machine learning to analyze how dopamine dynamics in the dorsal and ventral striatum of mice correlate with behavioral patterns during exploratory behavior.