Roopesh Anand

This study shows TRF2 mediates force-resistant tethering of telomeric DNA repeats, which may be a step in T-loop formation.

This study identifies a germline BRIP1 variant linked to childhood cancer, showing it causes genomic instability and creates therapeutic vulnerabilities.

This study identifies APE2 nuclease as a critical factor for MMEJ repair, showing its role in telomere fusion and DNA repair reporter assays.

This study identifies MCM8IP as a DNA repair factor that promotes homologous recombination and DNA synthesis in response to DNA damage by interacting with MCM8-9 and RPA1.