Zhou Xu

The paper develops a mathematical model to infer telomere dynamics parameters from telomere length distributions in yeast using long-read sequencing data.

The paper identifies centromeres as a source of telomeric sequences in Arabidopsis, showing ITR domains arise from centromeres through amplification and adopt a distinct chromatin state.

The paper catalogs Y' elements in S. cerevisiae, revealing structural diversity and a potential role in telomere length regulation.

The paper analyzes telomere length distributions in 100 Saccharomyces cerevisiae strains, revealing diversity influenced by ploidy, subtelomere structure, and Y element content.

This study shows that transient telomere uncapping in yeast causes genomic rearrangements and telomere elongation, with implications for genome stability and evolution.

This study identifies a CST complex-mediated post-resection NHEJ repair pathway that promotes intermediate deletions while preventing larger deletions and rearrangements.

This study develops a mathematical model to link telomere length and replicative senescence in yeast, revealing population dynamics and factors affecting proliferation capacity.

The paper uses long-read sequencing to study genome rearrangements in telomerase mutants of Chlamydomonas reinhardtii, revealing complex subtelomere dynamics and alternative mechanisms for chromosome stability.

This study investigates how the Polo kinase Cdc5 is regulated during adaptation to telomere dysfunction in yeast, showing that its levels and phosphorylation status are critical for maintaining long-term cell cycle arrest.

The paper introduces DNA Drive, a biosafe and biocompatible DNA data storage strategy with unlimited storage capacity, encoding historical texts from the French Revolution.

The paper develops an optimized protocol to extract high-molecular-weight DNA from Chlamydomonas reinhardtii for long-read sequencing, validated with Oxford Nanopore Technologies.

The paper models non-terminal cell cycle arrests in telomerase-negative yeast to show they arise from a generation-dependent process distinct from terminal senescence.

This study models how delayed and variable adaptation to DNA damage can enhance population survival in fluctuating environments but also increase genome instability.

The paper describes the subtelomere architecture in Chlamydomonas reinhardtii using long-read sequencing and identifies repeated elements and their evolutionary dynamics.