Author

Guomei Tang

Columbia University Irving Medical CenterORCID 0000-0001-9479-5331Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

Alice Lau· 1 shared Alice Tang· 1 shared Andrea M. Reyes-OrtiziD· 1 shared Benjamin D. HobsoniD· 1 shared David L. SulzeriD· 1 shared David K. DansuiD· 1 shared Emily MiyoshiiD· 1 shared Ernest FraenkeliD· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperNeuroscience

Alice Lau

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2 papers

Recent·Most cited

Single nuclei RNAseq analysis of HD mouse models and human brain reveals impaired oligodendrocyte maturation and potential role for thiamine metabolism

Ryan G. Lim, Osama Al‐Dalahmah, Jie Wu, Maxwell P. Gold, Jack C. Reidling, Guomei Tang, Miriam Adam, David K. Dansu, Hye-Jin Park, Patrizia Casaccia, Ricardo Miramontes, Andrea M. Reyes-Ortiz, Alice Lau, Fatima Khan, Fahad Paryani, , Leslie Michels Thompson

This study uses snRNAseq to analyze HD mouse models and human brain tissue, identifying impaired oligodendrocyte maturation and a potential role for thiamine metabolism in disease pathology.

bioRxiv · Jun 27, 2022 · PreprintNeuroscience

Widespread Alterations in Translation Elongation in the Brain of Juvenile Fmr1 Knock-Out Mice

Sohani Das Sharma, Jordan B. Metz, Hongyu Li, Benjamin D. Hobson, Nicholas J. Hornstein, David L. Sulzer, Guomei Tang, Peter A. Sims

This study uses ribosome profiling to show that Fmr1 loss in mice affects translation elongation and initiation, with reduced pausing and altered mRNA binding.

Cell Reports · Mar 1, 2019Peer-reviewedMolecular Biology