Author

Paraskevi Athanasouli

Leuven Stem Cell InstituteORCID 0000-0001-9504-7562Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Approach:statistical model· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Frederic Lluı́siD· 3 shared Alessandra QualizzaiD· 2 shared Anchel De Jaime-SogueroiD· 2 shared Bernard K. van der VeeriD· 2 shared Catherine M. VerfaillieiD· 2 shared Kian Peng KohiD· 2 shared Youssef El LaithyiD· 2 shared Adrian JaniszewskiiD· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersDevelopmental Biology

Frederic Lluı́sORCID

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3 papers

Recent·Most cited

Cancer BiologyCancer ResearchPeer-reviewedOct 21, 2025

Chemotherapy-treated breast cancer cells activate the Wnt signaling pathway to enter a diapause-DTP state.

Youssef El Laithy, Willy Antoni Abreu de Oliveira, Anirudh Pabba…·Frederic Lluís

This study shows chemotherapy induces a Wnt-active diapause-DTP state in breast cancer cells, which can be targeted by combined Wnt and chemotherapy inhibition.

6 citations

humanbulk RNA-seq

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Developmental BiologyAdvanced SciencePeer-reviewedDec 1, 2023

Osmolar modulation drives reversible cell cycle exit and human pluripotent cell differentiation via NF-κB and WNT signaling

Jonathan Sai‐Hong Chui, Teresa Izuel Idoype, Alessandra Qualizza…·Frederic Lluı́s

This study shows that hyperosmolar conditions induce cell cycle exit and differentiation in pluripotent cells through NF-κB and WNT signaling pathways.

6 citations

humanbulk RNA-seq

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Developmental BiologyNature CommunicationsPeer-reviewedMar 3, 2023

The Wnt/TCF7L1 transcriptional repressor axis drives primitive endoderm formation by antagonizing naive and formative pluripotency

Paraskevi Athanasouli, Martina Balli, Anchel De Jaime-Soguero…·Frederic Lluı́s

This study shows that Wnt/TCF7L1 repression promotes primitive endoderm differentiation in mESCs by inhibiting naive and formative pluripotency factors.

31 citations

mousebulk RNA-seq

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