Víctor A. Tallada

This study shows that EMC complex dysfunction in fission yeast impairs mitochondrial respiration and quiescence, with rescue via membrane fluidity and sterol composition changes.

This study shows EMC facilitates membrane protein biogenesis by regulating membrane fluidity through ergosterol homeostasis in fission yeast.

The paper identifies age-related genome rearrangements in non-dividing fission yeast cells, linking them to R-loops and regulatory changes, and finds similar patterns in human brain cells.

The paper evaluates ENU as a mutagen in fission yeast, showing it induces base changes and identifies mutants with potential applications in metabolism and antibiotic resistance.

The paper uses transposon mutagenesis and a hidden Markov model to identify functional elements in the fission yeast genome, finding that 90% of the genome has fitness consequences.