Peter Bross

The paper shows sortilin mediates neuronal uptake of fatty acids via apoE, enabling their use as metabolic fuel, but this pathway is disrupted by apoE4, linked to Alzheimer's risk.

This study identifies that combining DHODH inhibition with BCL-XL targeting synergistically induces apoptosis in pancreatic cancer, offering a new combination therapy strategy.

This study investigates how HSP60 deficiency disrupts mitochondrial proteostasis and dysregulates cholesterol synthesis, leading to developmental abnormalities and hypomyelination.