Arnab Gupta

This paper introduces Gua-Cu-3, a dual-function molecule that sequesters copper and reduces oxidative stress in Wilson disease models, outperforming existing treatments.

This study identifies conserved inter-domain interactions critical for TGN localization and copper trafficking in Cu-ATPases by analyzing chimeric proteins and evolutionary relationships.

This paper evaluates melatonin as a dual-function therapeutic for Wilson disease, showing it reduces copper toxicity and oxidative stress in vitro and in vivo.

This study identifies a non-canonical receptor-like mechanism where CTR1 clusters on the plasma membrane in response to copper, modulating membrane properties to facilitate endocytosis.