Yifu Han

This study shows that expressing G4C2 repeats in Drosophila mushroom bodies causes age-dependent TDP-43 pathology and dementia-like phenotypes, with Dlp/GPC6 playing a role in synaptic loss.

The paper introduces GCaMP8 variants targeted to synaptic compartments and develops CaFire software to quantify Ca2+ signals, showing improved sensitivity and resolution compared to existing methods.

The paper investigates how two distinct motor inputs contribute to presynaptic homeostatic plasticity (PHP) in Drosophila, showing input-specific mechanisms for stabilizing neuromuscular junction activity.

The paper identifies physiological and nanoscale differences in glutamatergic synapses between tonic and phasic neurons at the Drosophila neuromuscular junction.

This study uses botulinum neurotoxin to isolate neurotransmission from tonic and phasic neurons in Drosophila, revealing heterosynaptic plasticity rules.

This study shows that excess glutamate release selectively regulates GluR subtypes through competition and Ca2+ signaling in Drosophila.

This paper develops a hybrid chemical-genetic voltage reporter for voltage imaging in Drosophila, enabling selective neuron labeling and voltage monitoring in intact tissues.