João Jacob Ramalho

The paper identifies a conserved mechanism for polar protein targeting in plants using proteomics and shows PAT19 mediates SOSEKI1 membrane localization in Arabidopsis and other species.

This study shows that MpARF2 forms nanoclusters that enable high-affinity, switch-like, and sequence-specific DNA binding, distinct from monomeric or condensate-based mechanisms.

This study identifies GCK-4 as a regulator of apical actin and junction organization in C. elegans intestine lumen formation, showing it acts independently of ERM phosphorylation.

The paper identifies a novel fungal peptide from Ophiocordyceps that binds to scramblase channels in ants, disrupting motor coordination and olfactory systems.

The paper uses quantitative modeling to investigate fate specification in the C. elegans postembryonic M lineage and identifies potential missing spatiotemporal signals.

This study identifies MAGU-2 and MPZ-1 as C. elegans orthologs of Pals1 and PATJ, showing they form a Crumbs complex and are involved in apical domain formation.

The paper identifies BBLN-1 as a regulator of lumen morphology in C. elegans intestine and identifies its mammalian ortholog bublin, which can compensate for its loss.