Richard J Stopforth

This study shows CD1c-autoreactive T-cells recognize Mtb-infected APCs, exhibit cytotoxicity, and reduce Mtb burden through CD1c-dependent mechanisms.

This study identifies ABHD11 as a deglutarylating enzyme that regulates T cell metabolism by maintaining TCA cycle integrity through removal of glutaryl-lipoyl adducts.

This study shows that an inherited mtDNA mutation alters inflammatory cytokine responses in macrophages and in vivo, leading to increased IFN-I and reduced pro-inflammatory cytokines.