Ronen Spiegel

Early maturation and hyperexcitability is a shared phenotype of cortical neurons derived from different ASD-associated mutations

The paper shows that cortical neurons from ASD-associated mutations exhibit early maturation and hyperexcitability compared to controls.

Study of an FBXO7 patient mutation reveals Fbxo7 and PI31 co-regulate proteasomes and mitochondria

This study identifies an FBXO7 mutation that disrupts its interaction with PI31, affecting proteasome and mitochondrial function in patient cells.