Author

Samuel Collombet

European Molecular Biology LaboratoryORCID 0000-0002-0111-7177Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Research Focus:gene regulatory network inference· 3 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:trajectory inference· 2

Frequent Co-Authors

Adrian JaniszewskiiD· 1 shared Agnès Le Saux· 1 shared Alec Basil HeckertiD· 1 shared Aliaksandr A. HalavatyiiD· 1 shared Antonio GómeziD· 1 shared Bruno Di StefanoiD· 1 shared Caterina Provenzano· 1 shared Claire Dugast‐DarzacqiD· 1 shared

Activity by Year

2018-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperDevelopmental Biology

Adrian JaniszewskiORCID

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3 papers

Recent·Most cited

Developmental BiologyNature Structural & Molecular BiologyPeer-reviewedJun 8, 2023

RNA polymerase II depletion from the inactive X chromosome territory is not mediated by physical compartmentalization.

Samuel Collombet, Isabell Rall, Claire Dugast‐Darzacq…·Édith Heard

The paper shows that RNA polymerase II depletion from the inactive X chromosome is due to reduced chromatin binding, not biophysical compartmentalization.

44 citations

humanbulk RNA-seq

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Developmental BiologybioRxivFeb 9, 2019

Dynamic Erasure of Random X-Chromosome Inactivation during iPSC Reprogramming

Adrian Janiszewski, Irene Talón, Joel Chappell…·Vincent Pasque

This study investigates the dynamics of X-chromosome reactivation during mouse iPSC reprogramming, revealing hierarchical gene activation patterns and the role of chromatin regulators.

57 citations

mousebulk RNA-seq

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Molecular BiologyNature GeneticsPeer-reviewedJan 9, 2018

Transcription Factors Orchestrate Dynamic Interplay Between Genome Topology And Gene Regulation During Cell Reprogramming

Ralph Stadhouders, Enrique Vidal, François Serra…·Thomas Graf

The paper shows transcription factors drive genome topology changes before gene expression during cell reprogramming.

366 citationstop 1%

mouseChIP-seq

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