Author

Richard S. Van

University of OklahomaORCID 0000-0002-0185-9277Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:imaging· 2 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1 Organism:non-human primate· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

Erick Calderon Leon· 2 shared Yihan ShaoiD· 2 shared Ahmed HaideriD· 1 shared Astra YuiD· 1 shared Atsuto Hiraishi· 1 shared Biyue ZhuiD· 1 shared Can Martin ZhangiD· 1 shared Chongzhao RaniD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBiochemistry

Erick Calderon Leon

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2 papers

Recent·Most cited

Highly sensitive chemiluminescence imaging of misfolded proteins in neurodegenerative models

Biyue Zhu, Richard S. Van, Huizhe Wang, Shi Kuang, Yuntao Jia, Erick Calderon Leon, Jing Zhang, Jun Yang, Howard Hong, Fleur Lobo, Astra Yu, Johnson Wang, Rudolph E. Tanzi, Can Martin Zhang, Xiaobo Mao, , Chongzhao Ran

This paper introduces a chemiluminescence probe, ADLumin-1, that enables both generic and precise detection of misfolded proteins in neurodegenerative disease models.

bioRxiv · Apr 12, 2025 · PreprintBiochemistry

Radiosynthesis and preclinical evaluation of a carbon-11 labeled PDE7 inhibitor for PET neuroimaging

Zhiwei Xiao, Jiyun Sun, Masayuki Fujinaga, Huiyi Wei, Chunyu Zhao, Ahmed Haider, Richard S. Van, Tomoteru Yamasaki, Yiding Zhang, Jian Rong, Kuan Hu, Jiahui Chen, Erick Calderon Leon, Atsuto Hiraishi, Junjie Wei, , Steven H. Liang

This paper develops and evaluates [11C]26, a PET probe for imaging PDE7 in the brain, showing promising in vitro performance and moderate specific binding in nonhuman primates.

bioRxiv · Jun 12, 2021 · PreprintNeuroscience