Chunyu Zhao

This paper evaluates [18F]AZD9574, a PET radiotracer for imaging PARP-1, showing uptake correlated with PARP-1 expression and blocked by PARP inhibitors in cancer cell lines and xenograft models.

This study develops and evaluates [18F]P4B-2412 as a PET radioligand for imaging PDE4B, showing high binding, specificity, and metabolic stability in rodent models.

This study shows that N-acetylation of α-synuclein enhances its ability to cluster synaptic vesicles via increased interaction with lysophosphatidylcholine.

This paper develops and evaluates [11C]26, a PET probe for imaging PDE7 in the brain, showing promising in vitro performance and moderate specific binding in nonhuman primates.