Systematic mapping of genetic interactions for de novo fatty acid synthesis
Michael Aregger, Keith A. Lawson, Maximilian Billmann, Michael Costanzo, Amy H.Y. Tong, Katherine Chan, Mahfuzur Rahman, Kevin R. Brown, Catherine Ross, Matej Ušaj, Lucy Nedyalkova, Olga S. Sizova, Andrea Habsid, Judy Pawling, Zhen‐Yuan Lin, , Jason Moffat
This study maps genetic interactions in FASN-deficient cells to identify genes involved in lipid uptake and metabolic adaptation.
Nature Metabolism · Jun 1, 2020Peer-reviewedSystems Biology