Sina Wittmann

Active field theory approach to explain size control of transcriptional condensates

The paper uses microscopy and field theory to show transcriptional condensates exhibit size control through non-equilibrium dynamics.

Biomolecular condensates sustain pH gradients at equilibrium driven by charge neutralisation

This study shows that biomolecular condensates can sustain pH gradients without energy input by neutralizing charges, revealing their role in creating pH microenvironments.

Differential conformational expansion of Nup98-HOXA9 oncoprotein in micro- and macrophases

This study examines the conformational changes of Nup98-HOXA9's FG domain across different assembly states, revealing micelle-like structures and dynamic transitions during condensate formation.

Histone deacetylation promotes transcriptional silencing at facultative heterochromatin

The paper shows that HDAC-dependent histone deacetylation is critical for transcriptional silencing of facultative heterochromatin in fission yeast.