Trude Helen Flo

This study shows that cell-intrinsic complement C3 suppresses IFN-β production in macrophages by limiting IRF3-TBK1 complex formation.

This study identifies NINJ1 as a mediator of plasma membrane rupture in Mtb-infected macrophages, showing it operates independently of canonical cell death pathways and requires the ESX-1 secretion system.

This study uses in vivo microdialysis to longitudinally monitor Aβ and tau in AD mice, showing biomarker dynamics similar to human patients.