Author

Tiancheng Fang

Harvard UniversityORCID 0000-0002-0643-7209Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Alejandro Sweet-CorderoiD· 1 shared Catherine RheeiD· 1 shared David B. SykesiD· 1 shared David T. ScaddeniD· 1 shared J. Alex B. Gibbons· 1 shared Jonathan G. Van VrankeniD· 1 shared Jun Xia· 1 shared Lai Ping WongiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Alejandro Sweet-CorderoORCID

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1 paper

Recent·Most cited

Interrupting ELMSAN1 repression of nuclear Acetyl-CoA production therapeutically reprograms cancer cells

Ting Zhao, Lingli He, Lai Ping Wong, Shenglin Mei, Jun Xia, Yanxin Xu, Jonathan G. Van Vranken, Michael C. Mazzola, Lei Chen, Catherine Rhee, Tiancheng Fang, Tsuyoshi Fukushima, Leanne C. Sayles, Matthew Diaz, J. Alex B. Gibbons, , David T. Scadden

The paper identifies ELMSAN1 as a repressor of nuclear acetyl-CoA production and shows that inhibiting this interaction reprograms cancer cells to a postmitotic state, improving survival in multiple cancer models.

bioRxiv · Apr 25, 2025 · PreprintCancer Biology