Author

Andreas Rummel

Medizinische Hochschule HannoverORCID 0000-0002-0645-1641Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell-cell communication· 1 Approach:experimental assay· 1 Assay:imaging· 1 Organism:mouse· 1

Frequent Co-Authors

Ailisa BlumiD· 1 shared Anmin JiangiD· 1 shared Brett M. CollinsiD· 1 shared Christopher SmalliD· 1 shared Frédéric A. MeunieriD· 1 shared Giuseppe BalistreriiD· 1 shared James A. RaeiD· 1 shared Justin John Cooper-WhiteiD· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Ailisa BlumORCID

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1 paper

Recent·Most cited

Synaptotagmin 1 mediates toxicity of botulinum neurotoxin type A

Merja Joensuu, Parnayan Syed, Saber H. Saber, Vanessa Lanoue, Tristan P. Wallis, James A. Rae, Ailisa Blum, Rachel S. Gormal, Christopher Small, Shanley F. Longfield, Anmin Jiang, Stefan Mahrhold, Nadja Krez, Michael Alan Cousin, Ruby Cooper‐White, , Frédéric A. Meunier

This paper shows that botulinum neurotoxin type A (BoNT/A) toxicity relies on synaptotagmin 1 (Syt1), which forms nanoclusters with PSG and SV2 on neuronal membranes, enabling endocytic targeting and neuronal communication disruption.

The EMBO Journal · May 25, 2023Peer-reviewedNeuroscience